乙醇脱氢酶5抗体（）

英文名称： Anti-ADH5 

浓度： 1mg/1ml 

抗体来源： Rabbit

克隆类型：polyclonal 

交叉反应：   Human, Mouse, Rat,   

产品类型: 一抗  

性    状:  Lyophilized or Liquid 

保存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

产品介绍 ：The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 （alcohol dehydrogenase 5 （class III））, also known as FDH （formaldehyde dehydrogenase）, ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.

Function : Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-（hydroxymethyl） glutathione.
Subunit : Homodimer.
Subcellular Location : Cytoplasm.
Similarity : Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Database links : UniProtKB/Swiss-Prot: P11766.4