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Frozen Cells validated for calcium testing: Serotonin 5-HT2A receptor, human recombinant, in CHO-K1 host cell. We provide one vial of frozen cells (10 million cells/vial). Some of our Frozen cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale.
Features:
The AequoScreen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.
The frozen cells approach to functional testing consists in the dissociation of cell culture from testing. That means that we will culture the cells and freeze them with an optimized protocol to stop all replication. These cells are then stored in liquid nitrogen or simply in a -80°C freezer, thawed and used directly in a functional, cellular GPCR test with previously validated performance.
检测目标类 | GPCR |
---|---|
检测目标类型 | Cell line |
检测验证 | Calcium Luminescence |
G-Alpha偶联蛋白 | Ga16 |
G-Alpha天然受体 | Gq/G11 |
宿主细胞 | CHO-K1 |
产品品牌名称 | AequoZen |
受体类型 | 5-Hydroxytryptamine (Serotonin) |
第二信使释放 | Calcium flux |
运输条件 | 干冰 |
治疗领域 | Central Nervous System, Cardiovascular |
产品尺寸 | 10 million cells |
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